{"id":848,"date":"2018-09-25T14:54:17","date_gmt":"2018-09-25T18:54:17","guid":{"rendered":"http:\/\/www.dysautonomiainternational.org\/blog\/wordpress\/?p=848"},"modified":"2018-09-25T14:54:34","modified_gmt":"2018-09-25T18:54:34","slug":"100000-research-grant-to-study-brain-fog-in-pots","status":"publish","type":"post","link":"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/100000-research-grant-to-study-brain-fog-in-pots\/","title":{"rendered":"$100,000 Research Grant to Study Brain Fog in POTS"},"content":{"rendered":"<div class=\"\" data-block=\"true\" data-editor=\"d99iq\" data-offset-key=\"8lrao-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"8lrao-0-0\"><span data-offset-key=\"8lrao-0-0\"><span data-text=\"true\">Dysautonomia International is pleased to issue a $100,000 grant to Dr. Jessica Eccles, NIHR Clinical Lecturer at Brighton and Sussex Medical School in the UK, to study brain fog in POTS.<\/span><\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"d99iq\" data-offset-key=\"bjnri-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"bjnri-0-0\"><span data-offset-key=\"bjnri-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"d99iq\" data-offset-key=\"91c5-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"91c5-0-0\"><span data-offset-key=\"91c5-0-0\"><span data-text=\"true\">POTS, an under-studied disorder, is characterized by clinical symptoms such as lightheadedness, fatigue, shortness of breath, tremors, heart palpitations and fainting or near-fainting upon moving from a prone to upright position. In addition to symptoms related to the autonomic nervous system, patients frequently describe brain fog \u2013 a strong sense of difficulty when thinking and concentrating. <\/span><\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"d99iq\" data-offset-key=\"1pkss-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"1pkss-0-0\"><span data-offset-key=\"1pkss-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"d99iq\" data-offset-key=\"f7d0i-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"f7d0i-0-0\">\n<p><span data-offset-key=\"f7d0i-0-0\"><span data-text=\"true\">\u201cResearch suggests that almost all patients with POTS experience this disabling symptom \u2013 however the mechanisms underpinning brain fog and its impact on quality of life are currently very poorly understood,\u201d Dr. Eccles said. \u201cWith this grant from Dysautonomia International, I will seek to address this problem by understanding the brain-body mechanisms involved in brain fog.\u201d<\/span><\/span><\/p>\n<\/div>\n<\/div>\n<div class=\"_1mf _1mj\" data-offset-key=\"f7d0i-0-0\">\n<figure id=\"attachment_850\" aria-describedby=\"caption-attachment-850\" style=\"width: 602px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-content\/uploads\/2018\/09\/Screen-Shot-2018-09-25-at-2.48.56-PM.png\" rel=\"attachment wp-att-850\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-850 \" src=\"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-content\/uploads\/2018\/09\/Screen-Shot-2018-09-25-at-2.48.56-PM-1024x548.png\" alt=\"Screen Shot 2018-09-25 at 2.48.56 PM\" width=\"602\" height=\"322\" srcset=\"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-content\/uploads\/2018\/09\/Screen-Shot-2018-09-25-at-2.48.56-PM-1024x548.png 1024w, https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-content\/uploads\/2018\/09\/Screen-Shot-2018-09-25-at-2.48.56-PM-300x160.png 300w, https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-content\/uploads\/2018\/09\/Screen-Shot-2018-09-25-at-2.48.56-PM-768x411.png 768w, https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-content\/uploads\/2018\/09\/Screen-Shot-2018-09-25-at-2.48.56-PM.png 1324w\" sizes=\"auto, (max-width: 602px) 100vw, 602px\" \/><\/a><figcaption id=\"caption-attachment-850\" class=\"wp-caption-text\">Dr. Eccles in her lab at Brighton and Sussex Medical School<\/figcaption><\/figure>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"d99iq\" data-offset-key=\"blt4a-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"blt4a-0-0\"><span data-offset-key=\"blt4a-0-0\"><span data-text=\"true\">POTS mainly affects women (about 85% of cases). Patients with POTS often experience thinking difficulties when the autonomic nervous system is challenged by being placed on a tilt table or standing, and there are also accompanying changes in blood flow in the brain. Dr. Eccles believes that that brain fog may arise in a similar way, and hopes this project can further explore this area by combing such techniques with non-invasive imaging of the brain \u2013 use of an electroencephalogram (EEG) and magnetic resonance imaging (MRI). <\/span><\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"d99iq\" data-offset-key=\"e9pjd-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"e9pjd-0-0\"><span data-offset-key=\"e9pjd-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"d99iq\" data-offset-key=\"1uqkv-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"1uqkv-0-0\"><span data-offset-key=\"1uqkv-0-0\"><span data-text=\"true\">Dr. Eccles explained, \u201crecent data from brain scans shows that challenging the autonomic nervous system in a similar way to standing changes blood flow in the brain in otherwise healthy individuals. Prior research demonstrates that POTS patients have altered blood flow to the brain when they stand. We think this may well be why patients with POTS experience brain fog.\u201d <\/span><\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"d99iq\" data-offset-key=\"709l4-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"709l4-0-0\"><span data-offset-key=\"709l4-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"d99iq\" data-offset-key=\"a5fki-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"a5fki-0-0\"><span data-offset-key=\"a5fki-0-0\"><span data-text=\"true\">Dr. Eccles hopes her research will help increase knowledge among patients and doctors alike. \u201cWe believe that this project will be relevant to finding and personalizing treatments to individuals with POTS, brain fog and also patients with other conditions related to the autonomic nervous system. Potentially, this will bring relief from a considerably disabling symptom that has a significant impact on quality of life for patients living with these conditions.\u201d<\/span><\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"d99iq\" data-offset-key=\"849t7-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"849t7-0-0\"><span data-offset-key=\"849t7-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"d99iq\" data-offset-key=\"4drql-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"4drql-0-0\"><span data-offset-key=\"4drql-0-0\"><span data-text=\"true\">Lauren Stiles, Esq., President of Dysautonomia International, added, \u201cDysautonomia International is pleased to support the innovative POTS research occurring at Brighton and Sussex Medical School, led by Dr. Eccles. Gaining a better understanding of brain functioning in POTS may help us identify better treatment options for millions of people around the world living with POTS.\u201d<\/span><\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"d99iq\" data-offset-key=\"f2sta-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"f2sta-0-0\"><span data-offset-key=\"f2sta-0-0\">\u00a0<\/span><\/div>\n<\/div>\n<div class=\"\" data-block=\"true\" data-editor=\"d99iq\" data-offset-key=\"ed07r-0-0\">\n<div class=\"_1mf _1mj\" data-offset-key=\"ed07r-0-0\"><span data-offset-key=\"ed07r-0-0\"><span data-text=\"true\">You can help Dysautonomia International fund even more amazing POTS research by making a contribution at\u00a0<span style=\"color: #00ccff;\"><strong><a style=\"color: #00ccff;\" href=\"http:\/\/www.CurePOTS.org\" target=\"_blank\">www.CurePOTS.org<\/a><\/strong><\/span>.<\/span><\/span><\/div>\n<div class=\"_1mf _1mj\" data-offset-key=\"ed07r-0-0\"><\/div>\n<\/div>\n<a 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width=\"16\" height=\"16\" style=\"display: inline;width:16px;height:16px;margin: 0;padding: 0;border: none;box-shadow: none\" src=\"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-content\/plugins\/social-media-feather\/synved-social\/image\/social\/regular\/32x32\/mail.png\" \/><\/a><a class=\"synved-social-credit\" target=\"_blank\" rel=\"nofollow\" title=\"WordPress Social Media Feather\" href=\"http:\/\/synved.com\/wordpress-social-media-feather\/\" style=\"color:#444;text-decoration:none;font-size:8px;margin-left:5px;vertical-align:10px;white-space:nowrap\"><span>by <\/span><img loading=\"lazy\" decoding=\"async\" style=\"display: inline;margin:0;padding:0;width:16px;height:16px\" width=\"16\" height=\"16\" alt=\"feather\" src=\"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-content\/plugins\/social-media-feather\/synved-social\/image\/icon.png\" \/><\/a>","protected":false},"excerpt":{"rendered":"<p>Dysautonomia International is pleased to issue a $100,000 grant to Dr. Jessica Eccles, NIHR Clinical Lecturer at Brighton and Sussex Medical School in the UK, to study brain fog in POTS. \u00a0 POTS, an under-studied disorder, is characterized by clinical symptoms such as lightheadedness, fatigue, shortness of breath, tremors, heart palpitations and fainting or near-fainting &hellip; <a href=\"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/100000-research-grant-to-study-brain-fog-in-pots\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">$100,000 Research Grant to Study Brain Fog in POTS<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-848","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-json\/wp\/v2\/posts\/848","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-json\/wp\/v2\/comments?post=848"}],"version-history":[{"count":4,"href":"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-json\/wp\/v2\/posts\/848\/revisions"}],"predecessor-version":[{"id":854,"href":"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-json\/wp\/v2\/posts\/848\/revisions\/854"}],"wp:attachment":[{"href":"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-json\/wp\/v2\/media?parent=848"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-json\/wp\/v2\/categories?post=848"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dysautonomiainternational.org\/blog\/wordpress\/wp-json\/wp\/v2\/tags?post=848"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}